DISEASES

Disease-gene associations mined from literature

Literature associating PFN3 and nephrolithiasis

PFN3 [ENSP00000351379]

Profilin-3; Binds to actin and affects the structure of the cytoskeleton. Slightly reduces actin polymerization. Binds to poly-L-proline, phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol 4-phosphate (PtdIns(4)P). May be involved in spermatogenesis. ; Belongs to the profilin family.

Synonyms:  PFN3,  PFN3p,  hPFN3,  P60673,  P60673p ...

Linkouts:  STRING  Pharos  UniProt  OMIM