Literature associating ADIPOR2 and Froelich syndrome
ADIPOR2 [ENSP00000349616]
Adiponectin receptor protein 2; Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism . Required for normal body fat and glucose homeostasis. ADIPOQ-binding activates a signaling cascade that leads to increased PPARA activity, and ultimately to increased fatty acid oxidation and glucose uptake. Has intermediate affinity for globular and full-length adiponectin. Required for normal revascularization after chronic ischemia caused by severing of blood vessels (By similarity); Belongs to the ADIPOR family.
Synonyms: ADIPOR2, ADIPOR2p, hADIPOR2, Q86V24, Q86V24p ...