DISEASES

Disease-gene associations mined from literature

Literature associating MAGEA1 and melanoma

MAGEA1 [ENSP00000349085]

Melanoma-associated antigen 1; May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.

Synonyms:  MAGEA1,  MAGEA1p,  hMAGEA1,  P43355,  P43355p ...

Linkouts:  STRING  Pharos  UniProt  OMIM