DISEASES

Disease-gene associations mined from literature

Literature associating PIGR and exudative vitreoretinopathy

PIGR [ENSP00000348888]

Polymeric immunoglobulin receptor; This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.

Synonyms:  PIGR,  P01833,  P01833p,  hP01833,  1XED ...

Linkouts:  STRING  Pharos  UniProt  OMIM