DISEASES

Disease-gene associations mined from literature

Literature associating RNF220 and Venezuelan hemorrhagic fever

RNF220 [ENSP00000347548]

E3 ubiquitin-protein ligase RNF220; E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By similarity). Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7- mediated deubiquitination of CTNNB1 promoting Wnt signaling .

Synonyms:  RNF220,  RNF220p,  hRNF220,  H0Y7B1,  Q5TDE7 ...

Linkouts:  STRING  Pharos  UniProt