Literature associating ITSN2 and von Willebrand's disease
ITSN2 [ENSP00000347244]
Intersectin-2; Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs). Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR). Plays a role in dendrite formation by melanocytes .
Synonyms: ITSN2, ITSN2p, hITSN2, A0A087WVF7, E7EPJ2 ...