DISEASES

Disease-gene associations mined from literature

Literature associating ASGR2 and hepatitis E

ASGR2 [ENSP00000347140]

Asialoglycoprotein receptor 2; Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N- acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.

Synonyms:  ASGR2,  ASGR2p,  hASGR2,  I3L1H2,  P07307 ...

Linkouts:  STRING  Pharos  UniProt  OMIM