DISEASES

Disease-gene associations mined from literature

Literature associating MAK and retinitis pigmentosa 1

MAK [ENSP00000346484]

Serine/threonine-protein kinase MAK; Essential for the regulation of ciliary length and required for the long-term survival of photoreceptors (By similarity). Phosphorylates FZR1 in a cell cycle-dependent manner. Plays a role in the transcriptional coactivation of AR. Could play an important function in spermatogenesis. May play a role in chromosomal stability in prostate cancer cells; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

Synonyms:  MAK,  A0A140VK28,  P20794,  Q8IXN4,  P20794p ...

Linkouts:  STRING  Pharos  UniProt