DISEASES

Disease-gene associations mined from literature

Literature associating VPS72 and amyotrophic lateral sclerosis type 7

VPS72 [ENSP00000346464]

Vacuolar protein sorting-associated protein 72 homolog; Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling.

Synonyms:  VPS72,  VPS72p,  hVPS72,  A0A1W2PPT2,  Q15906 ...

Linkouts:  STRING  Pharos  UniProt