Literature associating DPY30 and Kabuki syndrome
DPY30 [ENSP00000345837]
Protein dpy-30 homolog; As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys- 4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport. ; Belongs to the dpy-30 family.
Synonyms: DPY30, DPY30p, hDPY30, Q9C005, Q9C005p ...