DISEASES

Disease-gene associations mined from literature

Literature associating CTSL and severe acute respiratory syndrome

CTSL [ENSP00000345344]

Cathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (Probable). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (By similarity).

Synonyms:  CTSL,  A0A024R276,  P07711,  Q5T8F0,  P07711p ...

Linkouts:  STRING  Pharos  UniProt