Literature associating SHANK2 and autosomal recessive nonsyndromic deafness 63
SHANK2 [ENSP00000345193]
SH3 and multiple ankyrin repeat domains protein 2; Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.
Synonyms: SHANK2, SHANK2p, hSHANK2, A0A087X158, A0A0A0MSQ6 ...