DISEASES

Disease-gene associations mined from literature

Literature associating ADCY2 and Reis-Bucklers corneal dystrophy

ADCY2 [ENSP00000342952]

Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling . Down-stream signaling cascades mediate changes in gene expression patterns and lead to increased IL6 production. Functions in signaling cascades downstream of the muscarinic acetylcholine receptors (By similarity). ; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Synonyms:  ADCY2,  ADCY2p,  hADCY2,  D6REB8,  H0YA58 ...

Linkouts:  STRING  Pharos  UniProt  OMIM