DISEASES

Disease-gene associations mined from literature

Literature associating SYDE1 and keratomalacia

SYDE1 [ENSP00000341489]

Rho GTPase-activating protein SYDE1; GTPase activator for the Rho-type GTPases. As a GCM1 downstream effector, it is involved in placental development and positively regulates trophoblast cells migration. It regulates cytoskeletal remodeling by controlling the activity of Rho GTPases including RHOA, CDC42 and RAC1 .

Synonyms:  SYDE1,  SYDE1p,  hSYDE1,  M0QXZ8,  M0R101 ...

Linkouts:  STRING  Pharos  UniProt