Literature associating BRAT1 and early infantile epileptic encephalopathy
BRAT1 [ENSP00000339637]
BRCA1-associated ATM activator 1; Involved in DNA damage response; activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress . Plays a role in regulating mitochondrial function and cell proliferation . Required for protein stability of MTOR and MTOR- related proteins, and cell cycle progress by growth factors . ECO:0000269|PubMed:22977523, ECO:0000269|PubMed:25070371,
Synonyms: BRAT1, BRAT1p, hBRAT1, F8WDN5, Q6PJG6 ...