DISEASES

Disease-gene associations mined from literature

Literature associating PLAUR and essential thrombocythemia

PLAUR [ENSP00000339328]

Urokinase plasminogen activator surface receptor; Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form; CD molecules

Synonyms:  PLAUR,  M0QX27,  M0QYR6,  M0R0H5,  M0R0L1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM