Literature associating NPHP3 and nephronophthisis 2
NPHP3 [ENSP00000338766]
Nephrocystin-3; Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements.
Synonyms: NPHP3, NPHP3p, hNPHP3, A0A0C4DG93, F2Z3A8 ...