DISEASES

Disease-gene associations mined from literature

Literature associating DGKH and adrenal medulla cancer

DGKH [ENSP00000337572]

Diacylglycerol kinase eta; Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). Plays a key role in promoting cell growth. Activates the Ras/B-Raf/C-Raf/MEK/ERK signaling pathway induced by EGF. Regulates the recruitment of RAF1 and BRAF from cytoplasm to membranes and their heterodimerization.

Synonyms:  DGKH,  A0A087WZ02,  A0A0D9SF65,  A0A0D9SFR6,  Q86XP1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM