DISEASES

Disease-gene associations mined from literature

Literature associating IL17F and fungal infectious disease

IL17F [ENSP00000337432]

Interleukin-17F; Ligand for IL17RA and IL17RC . The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC . Involved in stimulating the production of other cytokines such as IL6, IL8 and CSF2, and in regulation of cartilage matrix turnover (PubMed:11591732, PubMed:11591768, PubMed:11574464). Also involved in stimulating the proliferation of peripheral blood mononuclear cells and T-cells and in inhibition of angiogenesis . Plays a role in the induction of neutrophilia in the lungs and in the exacerbation of antigen-induced pulmonary allergic inflammation (By similarity). ECO:0000269|PubMed:11591732, ECO:0000269|PubMed:11591768,; Belongs to the IL-17 family.

Synonyms:  IL17F,  IL17Fp,  hIL17F,  Q96PD4,  Q96PD4p ...

Linkouts:  STRING  Pharos  UniProt  OMIM