DISEASES

Disease-gene associations mined from literature

Literature associating RBBP9 and corneal endothelial dystrophy

RBBP9 [ENSP00000336866]

Serine hydrolase RBBP9; Serine hydrolase whose substrates have not been identified yet . May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation . May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta through interaction with RB1 and the subsequent displacement of E2F1 .

Synonyms:  RBBP9,  RBBP9p,  hRBBP9,  O75884,  O75884p ...

Linkouts:  STRING  Pharos  UniProt  OMIM