DISEASES

Disease-gene associations mined from literature

Literature associating PDE2A and scrotum squamous cell carcinoma

PDE2A [ENSP00000334910]

cGMP-dependent 3',5'-cyclic phosphodiesterase; Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Plays an important role in growth and invasion of malignant melanoma cells (e.g. pseudomyxoma peritonei (PMP) cell line) .

Synonyms:  PDE2A,  PDE2Ap,  hPDE2A,  C9JPD5,  E9PEF1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM