DISEASES

Disease-gene associations mined from literature

Literature associating CYP2F1 and kidney hypertrophy

CYP2F1 [ENSP00000333534]

Cytochrome P450 2F1; May be involved in the metabolism of various pneumotoxicants including naphthalene. Is able to dealkylate ethoxycoumarin, propoxycoumarin, and pentoxyresorufin but possesses no activity toward ethoxyresorufin and only trace dearylation activity toward benzyloxyresorufin. Bioactivates 3-methylindole (3MI) by dehydrogenation to the putative electrophile 3-methylene-indolenine. ; Belongs to the cytochrome P450 family.

Synonyms:  CYP2F1,  CYP2F1p,  hCYP2F1,  A0A075B795,  H0YGI9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM