DISEASES

Disease-gene associations mined from literature

Literature associating MARCHF11 and autosomal dominant intellectual developmental disorder 44

MARCHF11 [ENSP00000333181]

E3 ubiquitin-protein ligase MARCHF11; E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May play a role in ubuquitin-dependent protein sorting in developmenting spermatids.

Synonyms:  MARCHF11,  A6NNE9,  H0Y9K6,  MARCH11,  A6NNE9p ...

Linkouts:  STRING  Pharos  UniProt  OMIM