DISEASES

Disease-gene associations mined from literature

Literature associating IZUMO1R and fallopian tube adenocarcinoma

IZUMO1R [ENSP00000332963]

Sperm-egg fusion protein Juno; Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for species-specific gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. Does not bind folate.

Synonyms:  IZUMO1R,  IZUMO1Rp,  hIZUMO1R,  A6ND01,  J3KNP7 ...

Linkouts:  STRING  Pharos  UniProt