DISEASES

Disease-gene associations mined from literature

Literature associating H2AC20 and primary hyperoxaluria

H2AC20 [ENSP00000332194]

Histone H2A type 2-C; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Synonyms:  H2AC20,  H2AC20p,  hH2AC20,  HIST2H2AC,  Q16777 ...

Linkouts:  STRING  Pharos  UniProt  OMIM