Literature associating H1-5 and frontometaphyseal dysplasia 2
H1-5 [ENSP00000330074]
Histone H1.5; Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).
Synonyms: H1-5, HIST1H1B, P16401, P16401p, hP16401 ...