DISEASES

Disease-gene associations mined from literature

Literature associating H1-5 and frontometaphyseal dysplasia 1

H1-5 [ENSP00000330074]

Histone H1.5; Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).

Synonyms:  H1-5,  HIST1H1B,  P16401,  P16401p,  hP16401 ...

Linkouts:  STRING  Pharos  UniProt  OMIM