DISEASES

Disease-gene associations mined from literature

Literature associating GLRX5 and alcohol-related neurodevelopmental disorder

GLRX5 [ENSP00000328570]

Glutaredoxin-related protein 5, mitochondrial; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters . Involved in protein lipoylation, acting in the pathway that provides an iron-sulfur cluster to lipoate synthase . Required for normal iron homeostasis. Required for normal regulation of hemoglobin synthesis by the iron- sulfur protein ACO1 . May protect cells against apoptosis due to reactive oxygen species and oxidative stress (By similarity).

Synonyms:  GLRX5,  GLRX5p,  hGLRX5,  A0A384MDT9,  H0YJM6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM