DISEASES

Disease-gene associations mined from literature

Literature associating DHRS4 and superior semicircular canal dehiscence

DHRS4 [ENSP00000326219]

Dehydrogenase/reductase SDR family member 4; Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha- dicarbonyl compounds with aromatic rings, such as pyrimidine-4- aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4- hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones (By similarity); Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Synonyms:  DHRS4,  DHRS4p,  hDHRS4,  F5GWZ1,  H0YNP7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM