DISEASES

Disease-gene associations mined from literature

Literature associating PGR and leiomyosarcoma

PGR [ENSP00000325120]

Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Depending on the isoform, progesterone receptor functions as transcriptional activator or repressor. [Isoform B]: Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.

Synonyms:  PGR,  A0A087WXR4,  A0A0J9YVP1,  P06401,  Q8NG42 ...

Linkouts:  STRING  Pharos  UniProt  OMIM