DISEASES

Disease-gene associations mined from literature

Literature associating MMP1 and localized scleroderma

MMP1 [ENSP00000322788]

22 kDa interstitial collagenase; Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X . In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity . ECO:0000269|PubMed:16807369, ECO:0000269|PubMed:2153297,

Synonyms:  MMP1,  MMP1p,  hMMP1,  P03956,  P03956p ...

Linkouts:  STRING  Pharos  UniProt  OMIM