DISEASES

Disease-gene associations mined from literature

Literature associating FGF8 and hypogonadism

FGF8 [ENSP00000321797]

Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system (PubMed:16384934, PubMed:16597617, PubMed:8663044). Plays a role in neurite outgrowth in hippocampal cells . ECO:0000269|PubMed:16597617, ECO:0000269|PubMed:21576111,; Belongs to the heparin-binding growth factors family.

Synonyms:  FGF8,  FGF8p,  hFGF8,  A0A087X1S5,  P55075 ...

Linkouts:  STRING  Pharos  UniProt  OMIM