DISEASES

Disease-gene associations mined from literature

Literature associating H2BC4 and Ehrlich tumor carcinoma

H2BC4 [ENSP00000321744]

Histone H2B type 1-C/E/F/G/I; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Synonyms:  H2BC4,  H2BC4p,  hH2BC4,  B2R4S9,  HIST1H2BC ...

Linkouts:  STRING  Pharos  UniProt