DISEASES

Disease-gene associations mined from literature

Literature associating ADGRE2 and vibratory urticaria

ADGRE2 [ENSP00000319883]

Adhesion G protein-coupled receptor E2; Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF. Signals probably through G-proteins. Is a regulator of mast cell degranulation . ECO:0000269|PubMed:22310662, ECO:0000269|PubMed:22575658,

Synonyms:  ADGRE2,  ADGRE2p,  hADGRE2,  B4DWB8,  M0QY55 ...

Linkouts:  STRING  Pharos  UniProt