DISEASES

Disease-gene associations mined from literature

Literature associating CLEC4M and severe acute respiratory syndrome

CLEC4M [ENSP00000316228]

C-type lectin domain family 4 member M; Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates. (Microbial infection) Acts as an attachment receptor for Hepatitis C virus. (Microbial infection) Acts as an attachment receptor for Human coronavirus 229E. (Microbial infection) Acts as an attachment receptor for Influenzavirus. (Microbial infection) Acts as an attachment receptor for West-nile virus. (Microbial infection) Acts as an attachment receptor for Marburg virus glycoprotein.

Synonyms:  CLEC4M,  CLEC4Mp,  hCLEC4M,  E7ENS9,  H7BXU4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM