DISEASES

Disease-gene associations mined from literature

Literature associating EDNRA and portal hypertension

EDNRA [ENSP00000315011]

Endothelin-1 receptor; Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

Synonyms:  EDNRA,  P25101,  P25101p,  hP25101,  1909 ...

Linkouts:  STRING  Pharos  UniProt  OMIM