Literature associating CASP2 and hypertrophic cardiomyopathy 1
CASP2 [ENSP00000312664]
Caspase-2 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival . Associates with PIDD1 and CRADD to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis in response to genotoxic stress .
Synonyms: CASP2, CASP2p, hCASP2, A0A087WYM1, A0A0S2Z3H1 ...