DISEASES

Disease-gene associations mined from literature

Literature associating PRG2 and Loeffler syndrome

PRG2 [ENSP00000312134]

Eosinophil granule major basic protein; Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA.

Synonyms:  PRG2,  PRG2p,  hPRG2,  P13727,  P13727p ...

Linkouts:  STRING  Pharos  UniProt  OMIM