Literature associating LTBP4 and supravalvular aortic stenosis
LTBP4 [ENSP00000311905]
Latent-transforming growth factor beta-binding protein 4; Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta. ; Belongs to the LTBP family.
Synonyms: LTBP4, LTBP4p, hLTBP4, A0A087WUU1, A0A087WVR1 ...