DISEASES

Disease-gene associations mined from literature

Literature associating CCDC85B and tick-borne relapsing fever

CCDC85B [ENSP00000311695]

Coiled-coil domain-containing protein 85B; Functions as a transcriptional repressor . May inhibit the activity of CTNNB1 in a TP53-dependent manner and thus regulate cell growth . May function in adipocyte differentiation, negatively regulating mitotic clonal expansion (By similarity). Plays a role in cell-cell adhesion and epithelium development through its interaction with proteins of the beta-catenin family (By similarity). ECO:0000250|UniProtKB:Q6PDY0, ECO:0000269|PubMed:17014843,

Synonyms:  CCDC85B,  CCDC85Bp,  hCCDC85B,  Q15834,  Q15834p ...

Linkouts:  STRING  Pharos  UniProt  OMIM