DISEASES

Disease-gene associations mined from literature

Literature associating TNFRSF10D and Li-Fraumeni syndrome 1

TNFRSF10D [ENSP00000310263]

Tumor necrosis factor receptor superfamily member 10D; Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway.

Synonyms:  TNFRSF10D,  Q9UBN6,  Q9UBN6p,  hQ9UBN6,  8793 ...

Linkouts:  STRING  Pharos  UniProt  OMIM