DISEASES

Disease-gene associations mined from literature

Literature associating KLF7 and distal hereditary motor neuronopathy type 2D

KLF7 [ENSP00000309570]

Krueppel-like factor 7; Transcriptional factor . Plays a critical role in neuronal morphogenesis and survival of sensory neurons (By similarity). Represses the corneal epithelium differentiation . Acts also as a metabolic regulator, by modulating insulin sensitivity in pancreatic beta cells and skeletal muscle cells . Inhibits transcriptional inducers of adipogenesis and has a repressive role in the expression of several adipokines, including leptin .

Synonyms:  KLF7,  KLF7p,  hKLF7,  A0A024R3X8,  C9JX20 ...

Linkouts:  STRING  Pharos  UniProt  OMIM