DISEASES

Disease-gene associations mined from literature

Literature associating LIPT2 and lactic acidosis

LIPT2 [ENSP00000309463]

Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes, which catalyze essential redox reactions . Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity); Belongs to the LipB family.

Synonyms:  LIPT2,  LIPT2p,  hLIPT2,  A6NK58,  H0YC96 ...

Linkouts:  STRING  Pharos  UniProt