DISEASES

Disease-gene associations mined from literature

Literature associating BPTF and lacrimal system cancer

BPTF [ENSP00000307208]

Nucleosome-remodeling factor subunit BPTF; Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors.

Synonyms:  BPTF,  A0A0A0MR81,  A0A2R8Y7Q1,  E7ETD6,  E9PE19 ...

Linkouts:  STRING  Pharos  UniProt  OMIM