DISEASES

Disease-gene associations mined from literature

Literature associating ADRA1B and ocular hypotension

ADRA1B [ENSP00000306662]

Alpha-1B adrenergic receptor; This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes. ; Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA1B sub-subfamily.

Synonyms:  ADRA1B,  ADRA1Bp,  hADRA1B,  A0A286YF88,  P35368 ...

Linkouts:  STRING  Pharos  UniProt  OMIM