Literature associating SPRR1B and Dowling-Degos disease
SPRR1B [ENSP00000306461]
Cornifin-B; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage; Belongs to the cornifin (SPRR) family.
Synonyms: SPRR1B, SPRR1Bp, hSPRR1B, P22528, P22528p ...