DISEASES

Disease-gene associations mined from literature

Literature associating ROBO4 and megalencephalic leukoencephalopathy with subcortical cysts 2B

ROBO4 [ENSP00000304945]

Roundabout homolog 4; Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins (By similarity). Involved in the maintenance of endothelial barrier organization and function .

Synonyms:  ROBO4,  ROBO4p,  hROBO4,  B4DYV8,  Q8WZ75 ...

Linkouts:  STRING  Pharos  UniProt  OMIM