DISEASES

Disease-gene associations mined from literature

Literature associating RETREG1 and epithelial recurrent erosion dystrophy

RETREG1 [ENSP00000304642]

Reticulophagy regulator 1; Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes . Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins . Required for long-term survival of nociceptive and autonomic ganglion neurons .

Synonyms:  RETREG1,  RETREG1p,  hRETREG1,  H0Y9U4,  Q9H6L5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM