DISEASES

Disease-gene associations mined from literature

Literature associating THOP1 and trypanosomiasis

THOP1 [ENSP00000304467]

Thimet oligopeptidase; Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the amyloid-beta precursor protein and generate amyloidogenic fragments.

Synonyms:  THOP1,  THOP1p,  hTHOP1,  K7EIK4,  K7EKB6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM