DISEASES

Disease-gene associations mined from literature

Literature associating REEP4 and hereditary spastic paraplegia 26

REEP4 [ENSP00000303482]

Receptor expression-enhancing protein 4; Microtubule-binding protein required to ensure proper cell division and nuclear envelope reassembly by sequestering the endoplasmic reticulum away from chromosomes during mitosis. Probably acts by clearing the endoplasmic reticulum membrane from metaphase chromosomes; Belongs to the DP1 family.

Synonyms:  REEP4,  REEP4p,  hREEP4,  E5RGS2,  E5RIB5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM